Efficient trans-Splicing of Mutated Spliced Leader Exons in Leishmania tarentolae
نویسندگان
چکیده
منابع مشابه
Spliced leader trans-splicing
on the forests, wildlife, and indigenous people of this area, WWF warns. It is not necessary to use this area as there is already a total of 2.3 million hectares of idle or derelict land available for palm oil plantations in Kalimantan, an area greater than the proposed plantation, WWF points out. In addition, oil palm is not recommended for planting in areas more than 200 metres above sea leve...
متن کاملSpliced-leader trans-splicing in freshwater planarians.
trans-Splicing, in which a spliced-leader (SL) RNA is appended to the most 5' exon of independently transcribed pre-mRNAs, has been described in a wide range of eukaryotes, from protozoans to chordates. Here we describe trans-splicing in the freshwater planarian Schmidtea mediterranea, a free-living member of the phylum Platyhelminthes. Analysis of an expressed sequence tag (EST) collection fro...
متن کاملThe evolution of spliced leader trans-splicing in nematodes.
Spliced leader trans-splicing occurs in many primitive eukaryotes including nematodes. Most of our knowledge of trans-splicing in nematodes stems from the model organism Caenorhabditis elegans and relatives, and from work with Ascaris. Our investigation of spliced leader trans-splicing in distantly related Dorylaimia nematodes indicates that spliced-leader trans-splicing arose before the nemato...
متن کاملSpliced leader RNA trans-splicing discovered in copepods.
Copepods are one of the most abundant metazoans in the marine ecosystem, constituting a critical link in aquatic food webs and contributing significantly to the global carbon budget, yet molecular mechanisms of their gene expression are not well understood. Here we report the detection of spliced leader (SL) trans-splicing in calanoid copepods. We have examined nine species of wild-caught copep...
متن کاملSpliced leader RNA-mediated trans-splicing in phylum Rotifera.
In kinetoplastids, Euglena, and four metazoan phyla, trans-splicing has been described as a mechanism for the generation of mature messenger RNAs (mRNAs): 5'-ends of precursor mRNAs are replaced by a short spliced leader (SL) exon from a small SL RNA. Although the full phylogenetic range is unknown, trans-splicing has not been found in vertebrates, insects, plants, or yeast. In animal groups wh...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.30.18689